@article{16902, author = {Mrkobrada M. and Chan M. and Nagele P. and Szczeklik W. and Devereaux P. and Alonso-Coello P. and Walsh M. and Berwanger O. and Villar J. and Wang C. and Jacka M. and Sigamani A. and Srinathan S. and Biccard B. and Tiboni M. and Pettit S. and Botto F. and Sessler D. and Thomas S. and Rodseth R. and Pearse R. and McQueen M. and Kavsak P. and Thorlacius L. and Buse G. and Hill S. and Cembrowski G. and de Miguel A. and Graham M. and Kueh J. and Li S. and Lit L. and Martinez-Bru C. and Naidoo P. and Xavier D. and Garcia M. and Chow Clara}, title = {High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study}, abstract = {

OBJECTIVES: To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay. DESIGN AND METHODS: We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults. RESULTS: Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT>/=14ng/L and 22% (95% CI:17-26%) had an elevation (>/=14ng/L) and change (>85%) in hs-TnT. CONCLUSION: Further research is needed to inform the optimal hs-TnT threshold and change in this setting.

}, year = {2011}, journal = {Clinical Biochemistry}, volume = {44}, edition = {2011/06/07}, number = {12}, pages = {1021-4}, isbn = {1873-2933 (Electronic)0009-9120 (Linking)}, note = {Kavsak, Peter AWalsh, MikeSrinathan, SadeeshThorlacius, LaurelBuse, Giovanna LuratiBotto, FernandoPettit, ShirleyMcQueen, Matthew JHill, Stephen AThomas, SabuMrkobrada, MarkoAlonso-Coello, PabloBerwanger, OtavioBiccard, Bruce MCembrowski, GeorgeChan, Matthew T VChow, Clara Kde Miguel, AngelesGarcia, MercedesGraham, Michelle MJacka, Michael JKueh, J HLi, Stephen C HLit, Lydia C WMartinez-Bru, CeciliaNaidoo, PrebashiniNagele, PeterPearse, Rupert MRodseth, Reitze NSessler, Daniel ISigamani, AlbenSzczeklik, WojciechTiboni, MariaVillar, Juan CarlosWang, C YXavier, DenisDevereaux, P JUnited StatesClinical biochemistryClin Biochem. 2011 Aug;44(12):1021-4. Epub 2011 May 24.}, language = {eng}, }