@article{21684,
  author = {Kohli H. and Ramachandran R. and Gupta K. and Jha V. and Nada R. and Kumar V and Kumar A. and Suri D. and Gupta A.},
  title = {Antibodies to m-type phospholipase A2 receptor in children with idiopathic membranous nephropathy},
  abstract = {<p>
Idiopathic membranous nephropathy (IMN), the commonest cause of adult nephrotic syndrome (NS), accounts for only a minority of paediatric NS. Antibodies to m-type phospholipase A2 receptor (PLA2R) are seen in two-thirds of adult IMN cases. PLA2R staining in glomerular deposits is observed in 74% and 45% of adult and paediatric IMN cases, respectively. However, there are no reports of anti-PLA2R in paediatric IMN. We evaluated anti-PLA2R levels and PLA2R in gloemrular deposits in paediatric IMN seen at our center. Five cases were enrolled, all the cases stained for PLA2R in glomeruli and three (60%) had antibodies to PLA2R antigen. There was a parellel reduction in proteinuria and anti-PLA2R titer. The present report suggests that PLA2R has a contributory role in the pathogenesis of paediatric IMN.
</p>
},
  year = {2015},
  journal = {Nephrology (Carlton)},
  volume = {20},
  edition = {2015/07/22},
  number = {8},
  pages = {572-5},
  isbn = {1440-1797 (Electronic)<br/>1320-5358 (Linking)},
  note = {Kumar, Vinod<br/>Ramachandran, Raja<br/>Kumar, Ashwani<br/>Nada, Ritambhra<br/>Suri, Deepti<br/>Gupta, Anju<br/>Kohli, Harbir Singh<br/>Gupta, Krishan Lal<br/>Jha, Vivekanand<br/>Australia<br/>Nephrology (Carlton). 2015 Aug;20(8):572-5. doi: 10.1111/nep.12478.},
  language = {eng},
}