@article{21865,
  author = {Bellomo R. and Cass A. and Gallagher M. and Martensson J. and Kaukonen K.},
  title = {Femoral Access and Delivery of Continuous Renal Replacement Therapy Dose},
  abstract = {<p>
AIMS: The study aims to describe the use of dialysis catheters in critically ill patients treated with continuous renal replacement therapy (CRRT) and to study the impact of femoral versus non-femoral access on CRRT dose. METHODS: Statistical analysis and predictive modelling of data from the Randomized Evaluation of Normal vs. Augmented Level renal replacement therapy trial. RESULTS: The femoral vein was the first access site in 937 (67%) of 1,399 patients. These patients had higher Acute Physiology and Chronic Health Evaluation and Sequential Organ Failure Assessment scores (p = 0.009) and lower pH (p &lt; 0.001) but similar mortality to patients with non-femoral access (44 vs. 45%; p = 0.63). Lower body weight was independently associated with femoral access placement (OR 0.97, 95% CI 0.96-0.98). Femoral access was associated with a 1.03% lower CRRT dose (p = 0.05), but a 4.20% higher dose was achieved with 13.5 Fr catheters (p = 0.03). CONCLUSIONS: Femoral access was preferred in lighter and sicker patients. Catheter gauge had greater impact than catheter site in CRRT dose delivery. Video Journal Club "Cappuccino with Claudio Ronco" at http://www.karger.com/?doi=439581.
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},
  year = {2015},
  journal = {Blood Purification},
  volume = {41},
  edition = {2015/10/21},
  number = {1-3},
  pages = {11-17},
  isbn = {1421-9735 (Electronic)<br/>0253-5068 (Linking)},
  note = {Bellomo, Rinaldo<br/>Martensson, Johan<br/>Lo, Serigne<br/>Kaukonen, Kirsi-Maija<br/>Cass, Alan<br/>Gallagher, Martin<br/>RENAL study investigators and the Australian and New Zealand Intensive Care Clinical Trials Group<br/>Blood Purif. 2015 Oct 20;41(1-3):11-17.},
  language = {Eng},
}