01156nas a2200157   4500000000100000008004100001100001600042700001100058700001400069700001900083700001500102245008900117250001500206520073100221020004600952       2012                            d1 aSullivan D.1 aJun M.1 aKotwal S.1 aPerkovic Vlado1 aNeal Bruce00aOmega 3 Fatty Acids and Cardiovascular Outcomes: Systematic Review and Meta-Analysis  a2012/11/013 a<p>
BACKGROUND: =0.24) or on total mortality (RR=0.95; 95% CI, 0.86-1.04; P=0.28). omega-3 FA did protect against vascular death (RR=0.86; 95% CI, 0.75-0.99; P=0.03) but not coronary events (RR=0.86; 95% CI, 0.67-1.11; P=0.24). There was no effect on arrhythmia (RR=0.99; 95% CI, 0.85-1.16; P=0.92) or cerebrovascular events (RR=1.03; 95% CI, 0.92-1.16; P=0.59). Adverse events were more common in the treatment group than the placebo group (RR=1.18, 95% CI, 1.02-1.37; P=0.03), predominantly because of an excess of gastrointestinal side effects.Conclusions-omega-3 FA may protect against vascular disease, but the evidence is not clear-cut, and any benefits are almost certainly not as great as previously believed.
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