01592nas a2200145   4500000000100000008004100001100002600042700001200068700001500080700001200095245013600107250001500243520114200258020004601400       2012                            d1 aSherrington Catherine1 aPaul S.1 aCanning C.1 aFung V.00aReproducibility of measures of leg muscle power, leg muscle strength, postural sway and mobility in people with Parkinson's disease  a2012/05/303 a<p>
Muscle power, muscle strength and postural sway are considered to be determinants of fall risk and gait in Parkinson's disease (PD) and potential targets for therapeutic trials. However, the potential usefulness of these tests as outcome measures depends on their reproducibility in the PD population. Therefore, measures of leg muscle power, leg muscle strength, postural sway and mobility were taken on two occasions 1week apart in 31 people with PD. Measures of muscle power, muscle strength and mobility were found to be very reliable (intraclass correlation coefficients (ICC(3,1) 0.50-0.97)) and showed good agreement, i.e. small measurement error. Postural sway measures showed poor reliability (ICC(3,1) 0.04-0.51) and agreement, especially in the presence of disabling dyskinesia. The moderate to high reproducibility of leg muscle power, muscle strength and mobility measures in people with PD confirm their suitability as outcomes measures in clinical and research settings. Further research into the clinical measurement of postural sway in people with PD is warranted, especially in individuals with dyskinesia.
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