01931nas a2200565 4500000000100000008004100001100001700042700001200059700001400071700001700085700001700102700002100119700001300140700001700153700001400170700001200184700001300196700001600209700001700225700001500242700001400257700001400271700001300285700001500298700001400313700001500327700001400342700001500356700001400371700001800385700001200403700001200415700001800427700001700445700001400462700001200476700001000488700001100498700002000509700001400529700001400543700001400557700001500571245011700586250001500703300001100718490000700729520058300736020004601319 2011 d1 aMrkobrada M.1 aChan M.1 aNagele P.1 aSzczeklik W.1 aDevereaux P.1 aAlonso-Coello P.1 aWalsh M.1 aBerwanger O.1 aVillar J.1 aWang C.1 aJacka M.1 aSigamani A.1 aSrinathan S.1 aBiccard B.1 aTiboni M.1 aPettit S.1 aBotto F.1 aSessler D.1 aThomas S.1 aRodseth R.1 aPearse R.1 aMcQueen M.1 aKavsak P.1 aThorlacius L.1 aBuse G.1 aHill S.1 aCembrowski G.1 ade Miguel A.1 aGraham M.1 aKueh J.1 aLi S.1 aLit L.1 aMartinez-Bru C.1 aNaidoo P.1 aXavier D.1 aGarcia M.1 aChow Clara00aHigh sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study a2011/06/07 a1021-40 v443 a

OBJECTIVES: To determine the proportion of noncardiac surgery patients exceeding the published 99th percentile or change criteria with the high sensitivity Troponin T (hs-TnT) assay. DESIGN AND METHODS: We measured hs-TnT preoperatively and postoperatively on days 1, 2 and 3 in 325 adults. RESULTS: Postoperatively 45% (95% CI: 39-50%) of patients had hs-TnT>/=14ng/L and 22% (95% CI:17-26%) had an elevation (>/=14ng/L) and change (>85%) in hs-TnT. CONCLUSION: Further research is needed to inform the optimal hs-TnT threshold and change in this setting.

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