01146nas a2200217 4500000000100000008004100001653001300042653001100055653001800066653001400084100001600098700001800114700001400132700001600146700001500162700001800177245006100195300001000256490000700266520065500273 2003 d10aDiabetes10asocial10ainternational10aEconomics1 aMonaghan H.1 aChaturvedi V.1 aCurrie R.1 aChalmers J.1 aNeal Bruce1 aPatel Anushka00aDiabetes and vascular disease: a new international trial a180-40 v113 a

The prevalence of diabetes is increasing, particularly in developing regions of the world. The social and economic consequences of this disease and its complications are enormous. We discuss the scope and implications of the increasing burden of diabetes and describe the rationale and design of a new international study examining blood pressure lowering and glucose control interventions aimed at reducing the risk of vascular complications in people with type 2 diabetes. This study is the first large-scale randomized trial in diabetes to include participants from both lower- and higher-income regions of the world. [References: 20]