01221nas a2200157   4500000000100000008004100001100001300042700001500055700001300070245006800083250001500151300001100166490000800177520082700185020005101012       2015                            d1 aEmdin C.1 aMacmahon S1 aRahimi K00aThe epidemiology of blood pressure and its worldwide management  a2015/03/15  a925-360 v1163 a<p>
Despite the vast amount of evidence on the benefits of blood pressure lowering accumulated to date, elevated blood pressure is still the leading risk factor for disease and disability worldwide. The purpose of this review is to summarize the epidemiological evidence underpinning the association between blood pressure and a range of conditions. This review focuses on the association between systolic and diastolic blood pressures and the risk of cardiovascular and renal disease. Evidence for and against the existence of a J-shaped curve association between blood pressure and cardiovascular risk, and differences in the predictive power of systolic, diastolic, and pulse pressure, are described. In addition, global and regional trends in blood pressure levels and management of hypertension are reviewed.
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  a1524-4571 (Electronic)<br/>0009-7330 (Linking)