02184nas a2200313   4500000000100000008004100001100001900042700001900061700002300080700001500103700001900118700001600137700001600153700001800169700001800187700002000205700002000225700002000245700001600265700002100281700002100302700002300323700001500346245010900361300001200470490000700482520136700489022001401856       2017                            d1 aAnderson Craig1 aLannin Natasha1 aCadilhac Dominique1 aKim Joosup1 aGrabsch Brenda1 aDewey Helen1 aHill Kelvin1 aGrimley Rohan1 aCastley Helen1 aMiddleton Sandy1 aBernhardt Julie1 aDonnan Geoffrey1 aFaux Steven1 aKilkenny Monique1 aLevi Christopher1 aBladin Christopher1 aHand Peter00aTreatment and Outcomes of Working Aged Adults with Stroke: Results from a National Prospective Registry.  a113-1200 v493 a<p><b>BACKGROUND: </b>Given the potential differences in etiology and impact, the treatment and outcome of younger patients (aged 18-64 years) require examination separately to older adults (aged ≥65 years) who experience acute stroke.</p><p><b>METHODS: </b>Data from the Australian Stroke Clinical Registry (2010-2015) including demographic and clinical characteristics, provision of evidence-based therapies and health-related quality of life (HRQoL) post-stroke was used. Descriptive statistics and multilevel regression models were used for group comparisons.</p><p><b>RESULTS: </b>Compared to older patients (age ≥65 years) among 26,220 registrants, 6,526 (25%) younger patients (age 18-64 years) were more often male (63 vs. 51%; p < 0.001), born in Australia (70 vs. 63%; p < 0.001), more often discharged home from acute care (56 vs. 38%; p < 0.001), and less likely to receive antihypertensive medication (61 vs. 73%; p < 0.001). Younger patients had a 74% greater odds of having lower HRQoL compared to an equivalent aged-matched general population (adjusted OR 1.74, 95% CI 1.56-1.93, p < 0.001).</p><p><b>CONCLUSIONS: </b>Younger stroke patients exhibited distinct differences from their older counterparts with respect to demographic and clinical characteristics, prescription of antihypertensive medications and residual health status.</p>  a1423-0208