Hypertension status among spouses is known to be concordant, but previous studies relied on history rather than direct measurement, and few data exist on treatment and control between spouses. The goal of this study was to estimate the spousal association of hypertension status, treatment, and control in adults. The authors identified and analyzed data on 4,500 pairs from the Atherosclerosis Risk in Communities (ARIC) cohort, which sampled middle-aged adults and their spouses in 1986-1989, with 3 follow-up visits 3 years apart. Generalized estimating equations were used in logistic regression analyses to calculate the odds ratio of a spouse's being hypertensive on the basis of the other spouse's hypertension status across 4 visits, adjusting for age, race, body mass index, smoking status, and sodium intake in both individuals. There are marginally increased odds of hypertension for spouses married to someone with hypertension (odds ratio (OR) = 1.15, 95% confidence interval (CI): 1.06, 1.25). Treatment was positively associated between spouses (OR = 1.35, 95% CI: 1.10, 1.67). Control was suggestive of an association, although it was not statistically significant (OR = 1.21, 95% CI: 0.93, 1.56). In middle-aged adults, hypertension status and treatment were moderately associated between spouses after controlling for shared environment. Physicians may target hypertension education and prevention to spouses as a pair rather than as 2 separate patients.
AD - Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA. mmcadams@jhsph.edu AN - 21841158 BT - American Journal of Epidemiology DA - 173246569349 ET - 2011/08/16 LA - eng M1 - 7 N1 - McAdams DeMarco, MaraCoresh, JosefWoodward, MarkButler, Kenneth RKao, W H LindaMosley, Thomas H JrHindin, MichelleAnderson, Cheryl A M5T32HL007024/HL/NHLBI NIH HHS/United StatesN01-HC-55015/HC/NHLBI NIH HHS/United StatesN01-HC-55016/HC/NHLBI NIH HHS/United StatesN01-HC-55018/HC/NHLBI NIH HHS/United StatesN01-HC-55019/HC/NHLBI NIH HHS/United StatesN01-HC-55020/HC/NHLBI NIH HHS/United StatesN01-HC-55021/HC/NHLBI NIH HHS/United StatesN01-HC-55022/HC/NHLBI NIH HHS/United StatesResearch Support, N.I.H., ExtramuralUnited StatesAmerican journal of epidemiologyAm J Epidemiol. 2011 Oct 1;174(7):790-6. Epub 2011 Aug 12. N2 -Hypertension status among spouses is known to be concordant, but previous studies relied on history rather than direct measurement, and few data exist on treatment and control between spouses. The goal of this study was to estimate the spousal association of hypertension status, treatment, and control in adults. The authors identified and analyzed data on 4,500 pairs from the Atherosclerosis Risk in Communities (ARIC) cohort, which sampled middle-aged adults and their spouses in 1986-1989, with 3 follow-up visits 3 years apart. Generalized estimating equations were used in logistic regression analyses to calculate the odds ratio of a spouse's being hypertensive on the basis of the other spouse's hypertension status across 4 visits, adjusting for age, race, body mass index, smoking status, and sodium intake in both individuals. There are marginally increased odds of hypertension for spouses married to someone with hypertension (odds ratio (OR) = 1.15, 95% confidence interval (CI): 1.06, 1.25). Treatment was positively associated between spouses (OR = 1.35, 95% CI: 1.10, 1.67). Control was suggestive of an association, although it was not statistically significant (OR = 1.21, 95% CI: 0.93, 1.56). In middle-aged adults, hypertension status and treatment were moderately associated between spouses after controlling for shared environment. Physicians may target hypertension education and prevention to spouses as a pair rather than as 2 separate patients.
PY - 2011 SN - 1476-6256 (Electronic)0002-9262 (Linking) SP - 790 EP - 6 T2 - American Journal of Epidemiology TI - Hypertension status, treatment, and control among spousal pairs in a middle-aged adult cohort VL - 174 ER -