TY - JOUR AU - Heeley E. AU - Zhao F. AU - Lu J. AU - Jiang X. AU - Guo X. AU - Guo L. AU - Li Y. AU - Zhang C. AU - Li Q. AU - Zhang R. AU - Zhang P. AU - Ji L. AU - McEvoy R. AU - Chai-Coetzer C. AU - Liu J. AU - Feng B. AU - Han P. AU - Sun L. AU - Dong S. AB -

Data on the prevalence of obstructive sleep apnea in subjects with type 2 diabetes mellitus in China is scarce. We conducted a multi-centre, cross-sectional study involving 12 hospitals from six regional cities to investigate the prevalence of obstructive sleep apnea in hospitalized patients with type 2 diabetes mellitus and to explore the association between obstructive sleep apnea and related risk factors, diabetic complications and comorbidities in China. Each hospital recruited at least 70 consecutive patients with type 2 diabetes mellitus who were admitted to the endocrinology ward. A total of 880 participants were enrolled and administered overnight sleep monitoring with a portable monitor (ApneaLink , ResMed, San Diego, CA, USA); other information was collected from medical charts and a standardized questionnaire. In this study, 60.0% (95% confidence interval: 56.8%, 63.2%) of hospitalized patients in China with type 2 diabetes mellitus had comorbid obstructive sleep apnea (apnea-hypopnea index >/= 5). Only 1.5% (eight of 528) of the patients with both conditions had been diagnosed previously with obstructive sleep apnea. The prevalence of moderate-severe (apnea-hypopnea index >/= 15) and severe obstructive sleep apnea (apnea-hypopnea index >/= 30) was estimated to be 25.6% (22.7, 28.5%) and 10.3% (8.3, 12.4%), respectively. Age, sex, body mass index, snoring, reported breath-holding in sleep or gasping or choking arousal, sleepiness, diabetes duration, hypertension, diabetic nephropathy and cardiovascular diseases history were correlated significantly with the severity of obstructive sleep apnea. In China, the prevalence of obstructive sleep apnea in hospitalized patients with type 2 diabetes mellitus is high. Routine screening for and treatment of obstructive sleep apnea is an important, but often neglected, part of the management of diabetes.

AD - The George Institute for Global Health at Peking University Health Science Center, Beijing, China.
Peking University People's Hospital, Beijing, China.
The George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, NSW, Australia.
Adelaide Institute for Sleep Health, Flinders University, Adelaide, SA, Australia.
Gansu Provincial Hospital, Lanzhou, China.
Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Shengjing Hospital of China Medical University, Shenyang, China.
The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Beijing Pinggu Hospital, Beijing, China.
The Third People's Hospital of Gansu Province, Lanzhou, China.
Shanghai Pudong New Area People's Hospital, Shanghai, China.
Sujiatun District Central Hospital, Shenyang, China.
Chongqing Donghua Hospital, Chongqing, China.
The Second Hospital of Zhanjiang City, Zhanjiang, China.
Beijing Hospital of Ministry of Health, Beijing, China. AN - 26268508 BT - Journal of Sleep Research DP - NLM ET - 2015/08/14 IS - 1 LA - Eng LB - CHINA
RSP
AUS N1 - Zhang, Puhong
Zhang, Rui
Zhao, Fang
Heeley, Emma
Chai-Coetzer, Ching L
Liu, Jing
Feng, Bo
Han, Ping
Li, Qifu
Sun, Liao
Li, Yufeng
Dong, Shengying
Jiang, Xiaozhen
Zhang, Chunhua
Lu, Jinhui
Guo, Xingduan
Guo, Lixin
Mcevoy, R Doug
Ji, Linong
J Sleep Res. 2015 Aug 13. doi: 10.1111/jsr.12334. N2 -

Data on the prevalence of obstructive sleep apnea in subjects with type 2 diabetes mellitus in China is scarce. We conducted a multi-centre, cross-sectional study involving 12 hospitals from six regional cities to investigate the prevalence of obstructive sleep apnea in hospitalized patients with type 2 diabetes mellitus and to explore the association between obstructive sleep apnea and related risk factors, diabetic complications and comorbidities in China. Each hospital recruited at least 70 consecutive patients with type 2 diabetes mellitus who were admitted to the endocrinology ward. A total of 880 participants were enrolled and administered overnight sleep monitoring with a portable monitor (ApneaLink , ResMed, San Diego, CA, USA); other information was collected from medical charts and a standardized questionnaire. In this study, 60.0% (95% confidence interval: 56.8%, 63.2%) of hospitalized patients in China with type 2 diabetes mellitus had comorbid obstructive sleep apnea (apnea-hypopnea index >/= 5). Only 1.5% (eight of 528) of the patients with both conditions had been diagnosed previously with obstructive sleep apnea. The prevalence of moderate-severe (apnea-hypopnea index >/= 15) and severe obstructive sleep apnea (apnea-hypopnea index >/= 30) was estimated to be 25.6% (22.7, 28.5%) and 10.3% (8.3, 12.4%), respectively. Age, sex, body mass index, snoring, reported breath-holding in sleep or gasping or choking arousal, sleepiness, diabetes duration, hypertension, diabetic nephropathy and cardiovascular diseases history were correlated significantly with the severity of obstructive sleep apnea. In China, the prevalence of obstructive sleep apnea in hospitalized patients with type 2 diabetes mellitus is high. Routine screening for and treatment of obstructive sleep apnea is an important, but often neglected, part of the management of diabetes.

PY - 2015 SE - 39-46 SN - 1365-2869 (Electronic)
0962-1105 (Linking) T2 - Journal of Sleep Research TI - The prevalence and characteristics of obstructive sleep apnea in hospitalized patients with type 2 diabetes in China VL - 25 Y2 - FY16 ER -