TY - JOUR AU - Kovoor P. AU - Zaman S. AU - Taylor A. AU - Stiles M. AU - Chow Clara AB -

The 'Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator Implantation to Prevent Tachyarrhythmias following Acute Myocardial Infarction' (PROTECT-ICD) trial is an Australian-led multicentre randomised controlled trial targeting prevention of sudden cardiac death in patients who have at least moderately reduced cardiac function following a myocardial infarct (MI). The primary objective of the trial is to assess whether electrophysiological study to guide prophylactic implantation of an implantable cardioverter-defibrillator (ICD) early following MI (first 40 days) will lead to a significant reduction in sudden cardiac death and non-fatal arrhythmia. The secondary objective is to assess the utility of cardiac MRI (CMR) in assessing early myocardial characteristics, and its predictive value for both inducible ventricular tachycardia (VT) at EPS and SCD/ non-fatal arrhythmia at follow-up.

AD - MonashHEART, Monash Medical Centre, Melbourne, Vic, Australia; Monash University, Melbourne, Vic, Australia.
Department of Cardiology, The Alfred Hospital, Melbourne, Vic, Australia; Baker IDI Heart and Diabetes Institute, Melbourne, Vic, Australia.
Waikato Hospital, Hamilton, New Zealand.
Department of Cardiology, Westmead Hospital, Sydney, NSW, Australia; The University of Sydney, Sydney, NSW, Australia; The George Institute for Global Health, Sydney, NSW, Australia.
Department of Cardiology, Westmead Hospital, Sydney, NSW, Australia; The University of Sydney, Sydney, NSW, Australia. Electronic address: pramesh.kovoor@sydney.edu.au. AN - 27522511 BT - Heart Lung Circ CN - [IF]: 1.438 DP - NLM ET - 2016/08/16 J2 - Heart, lung & circulation LA - eng LB - AUS
CDV
FY17 M1 - 11 N1 - Zaman, Sarah
Taylor, Andrew J
Stiles, Martin
Chow, Clara
Kovoor, Pramesh
Review
Australia
Heart Lung Circ. 2016 Nov;25(11):1055-1062. doi: 10.1016/j.hlc.2016.04.007. Epub 2016 May 6. N2 -

The 'Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator Implantation to Prevent Tachyarrhythmias following Acute Myocardial Infarction' (PROTECT-ICD) trial is an Australian-led multicentre randomised controlled trial targeting prevention of sudden cardiac death in patients who have at least moderately reduced cardiac function following a myocardial infarct (MI). The primary objective of the trial is to assess whether electrophysiological study to guide prophylactic implantation of an implantable cardioverter-defibrillator (ICD) early following MI (first 40 days) will lead to a significant reduction in sudden cardiac death and non-fatal arrhythmia. The secondary objective is to assess the utility of cardiac MRI (CMR) in assessing early myocardial characteristics, and its predictive value for both inducible ventricular tachycardia (VT) at EPS and SCD/ non-fatal arrhythmia at follow-up.

PY - 2016 SN - 1444-2892 (Electronic)
1443-9506 (Linking) SP - 1055 EP - 1062 ST - Heart Lung Circ T2 - Heart Lung Circ TI - Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator Implantation to Prevent Tachyarrhythmias following Acute Myocardial Infarction (PROTECT-ICD): Trial Protocol, Background and Significance VL - 25 Y2 - FY17 ER -