TY - JOUR AU - Anderson Craig AU - Lannin Natasha AU - Cadilhac Dominique AU - Kim Joosup AU - Grabsch Brenda AU - Dewey Helen AU - Hill Kelvin AU - Grimley Rohan AU - Castley Helen AU - Middleton Sandy AU - Bernhardt Julie AU - Donnan Geoffrey AU - Faux Steven AU - Kilkenny Monique AU - Levi Christopher AU - Bladin Christopher AU - Hand Peter AB -

BACKGROUND: Given the potential differences in etiology and impact, the treatment and outcome of younger patients (aged 18-64 years) require examination separately to older adults (aged ≥65 years) who experience acute stroke.

METHODS: Data from the Australian Stroke Clinical Registry (2010-2015) including demographic and clinical characteristics, provision of evidence-based therapies and health-related quality of life (HRQoL) post-stroke was used. Descriptive statistics and multilevel regression models were used for group comparisons.

RESULTS: Compared to older patients (age ≥65 years) among 26,220 registrants, 6,526 (25%) younger patients (age 18-64 years) were more often male (63 vs. 51%; p < 0.001), born in Australia (70 vs. 63%; p < 0.001), more often discharged home from acute care (56 vs. 38%; p < 0.001), and less likely to receive antihypertensive medication (61 vs. 73%; p < 0.001). Younger patients had a 74% greater odds of having lower HRQoL compared to an equivalent aged-matched general population (adjusted OR 1.74, 95% CI 1.56-1.93, p < 0.001).

CONCLUSIONS: Younger stroke patients exhibited distinct differences from their older counterparts with respect to demographic and clinical characteristics, prescription of antihypertensive medications and residual health status.

BT - Neuroepidemiology C1 - https://www.ncbi.nlm.nih.gov/pubmed/29136634?dopt=Abstract DO - 10.1159/000484141 IS - 3-4 J2 - Neuroepidemiology LA - eng N2 -

BACKGROUND: Given the potential differences in etiology and impact, the treatment and outcome of younger patients (aged 18-64 years) require examination separately to older adults (aged ≥65 years) who experience acute stroke.

METHODS: Data from the Australian Stroke Clinical Registry (2010-2015) including demographic and clinical characteristics, provision of evidence-based therapies and health-related quality of life (HRQoL) post-stroke was used. Descriptive statistics and multilevel regression models were used for group comparisons.

RESULTS: Compared to older patients (age ≥65 years) among 26,220 registrants, 6,526 (25%) younger patients (age 18-64 years) were more often male (63 vs. 51%; p < 0.001), born in Australia (70 vs. 63%; p < 0.001), more often discharged home from acute care (56 vs. 38%; p < 0.001), and less likely to receive antihypertensive medication (61 vs. 73%; p < 0.001). Younger patients had a 74% greater odds of having lower HRQoL compared to an equivalent aged-matched general population (adjusted OR 1.74, 95% CI 1.56-1.93, p < 0.001).

CONCLUSIONS: Younger stroke patients exhibited distinct differences from their older counterparts with respect to demographic and clinical characteristics, prescription of antihypertensive medications and residual health status.

PY - 2017 SP - 113 EP - 120 T2 - Neuroepidemiology TI - Treatment and Outcomes of Working Aged Adults with Stroke: Results from a National Prospective Registry. VL - 49 SN - 1423-0208 ER -